Topics in Molecular Genetics

Selected topics in molecular genetics and gene regulation, with a focus on examples from human evolution, physiology, and disease. The course will be organized into four modules with combined lecture and journal club-style discussion. Module topics include molecular regulation of transcription, epigenetic regulation of the genome, gene regulatory networks, and genome architecture and evolution. We will draw from examples in the current literature and explore current experimental approaches in molecular genetics of humans and model organisms.