Cell Biology

This course explores the components, systems, and regulatory mechanisms involved in eukaryotic cellular function. Topics include: signal transduction, translational and protein quality control, organellar and cytoskeletal dynamics, and some coordinated responses such as proliferation and programmed cell death. Throughout the course we will see how general cell biology can be specialized to achieve specific cellular functions through regulation of the basic machinery. We will also explore the cellular and molecular bases for a variety of human pathologies, with an emphasis on cancer. In addition to lecture, we will spend some time discussing the material, including selected articles from the primary literature, and learning through group presentations